CD151
Sign in to saveAlso known as GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24, CD151 molecule (Raph blood group), EBS7
CD151 molecule (Raph blood group), also known as CD151 (Cluster of Differentiation 151), is a human gene.
Gene data
CD151- Name
- CD151 molecule (Raph blood group)
- Type
- protein-coding
- Position
- 832,702–839,831 (+)
- Aliases
- EBS7, GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24
- Ensembl
- ENSG00000177697
- RefSeq RNA
- NM_001039490.2, NM_004357.5, NM_139029.2, NM_139030.4, XM_024448780.2
- RefSeq protein
- NP_001034579.1, NP_004348.2, NP_620598.1, NP_620599.1, XP_024304548.1
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
CD151 molecule (Raph blood group)
- Symbol
- CD151
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:832,702-839,831
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 20916
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/977
- genomic end
- 839831
- genomic start
- 832887
- chromosome
- human chromosome 11
- cytogenetic location
- 11p15.5
Sources (3)
via Wikidata · CC0
Article · Русский
CD151 — мембранный белок, гликопротеин из надсемейства тетраспанинов, продукт гена человека TSPAN24. Белок определяет группу крови системы RAPH.
Abstract from DBpedia / Wikipedia · CC BY-SA