Also known as CD8-receptor, CD8 antigens, CD8 molecule, CD8 receptor, CD8 protein
CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Along with the TCR, the CD8 co-receptor plays a role in T cell signaling and aiding with cytotoxic T cell-antigen interactions.
Key facts
- Protein family.Symbol
- CD8
- Protein family.Name
- Putative T-cell surface glycoprotein CD8
- Protein family.caption
- Crystallographic structure of the extracellular domain of CD8 molecule.
- Protein family.Membranome family
- 29
- Protein.Name
- CD8b molecule
- Protein.HGNCid
- 1707
- Protein.Symbol
- CD8B
- Protein.AltSymbols
- CD8B1
- Protein.EntrezGene
- 925
- Protein.OMIM
- 186910
- Protein.RefSeq
- NM_001768
- Protein.UniProt
- P01732
- Protein.Chromosome
- 2
- Protein.Arm
- p
- Protein.Band
- 12
via Wikipedia infobox
Research
147,223 papers- Effects of altered glycolysis levels on CD8(+) T cell activation and function.Cell death & disease · 2023
- CD8(+) T Cells in Atherosclerosis.Cells · 2020
- Lipids for CD8(+) TILs: Beneficial or harmful?Frontiers in immunology · 2022
- CD8(+) Tregs revisited: A heterogeneous population with different phenotypes and properties.European journal of immunology · 2021
- CD69(+)CD103(+)CD8(+) tissue-resident memory T cells possess stronger anti-tumor activity and predict better prognosis in colorectal cancer.Cell communication and signaling : CCS · 2024
via PubMed
Connections
B-cell
Entity
natural killer cell
Entity
human chromosome 2
Entity
T-cell receptor
Entity
CD1
Entity
Sialyl-Lewis X
Entity
TFRC
Gene
CD247
Gene
CD3E
Gene
protein
Entity
International Standard Book Number
Entity
digital object identifier
Entity
International Standard Serial Number
Entity
Q180686
Entity
lymphocyte
Entity
antigen
Entity
T-lymphocytes
Entity
National Center for Biotechnology Information
Entity
Q229883
Entity
glycoprotein
Entity