CD79b molecule
Sign in to saveAlso known as immunoglobulin-associated B29 protein, Ig-beta, B-cell antigen receptor complex-associated protein beta chain, CD79b molecule, immunoglobulin-associated beta, CD79b antigen (immunoglobulin-associated beta), CD79B, B-cell-specific glycoprotein B29
CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene.
Protein · UniProt
B-cell antigen receptor complex-associated protein beta chain
- Gene
- CD79B
- Organism
- Homo sapiens (Human)
- Length
- 229 aa
- Molecular mass
- 26,048 Da
- Evidence
- 1: Evidence at protein level
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation
Swiss-Prot (reviewed) · via UniProt
Clinical Trials
1 registered- PHASE1COMPLETEDPhase 1 Study of MGD010 in Healthy SubjectsMacroGenics · NCT02376036
~1 min read
Encyclopedic overview
4 sectionsContents
- See also
- References
- Further reading
- External links
CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene.
It is associated with agammaglobulinemia-6.
Excerpted from Wikipedia’s “CD79b molecule” article, available under the CC BY-SA 4.0 licence.