CDK5RAP3

Also known as C53, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114, PP1553, CDK5 regulatory subunit associated protein 3

CDK5 regulatory subunit-associated protein 3 is a protein that in humans is encoded by the CDK5RAP3 gene.

Gene data

CDK5RAP3

Name: CDK5 regulatory subunit associated protein 3
Type: protein-coding
Aliases: C53, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114, PP1553

This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013].

via MyGene.info

Wikidata facts

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HomoloGene ID: 12718
exact match: identifiers.org/ncbigene/80279
genomic end: 47981781
genomic start: 46045176
cytogenetic location: 17q21.32

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CDK5 regulatory subunit-associated protein 3 is a protein that in humans is encoded by the CDK5RAP3 gene.

Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation.