Structure via PubChem · Public domain (PubChem)
cefaclor
Sign in to saveAlso known as Ceclor, Panacef, Alfatil, CCL, Céfeaclor, Cefaclor anhydrous, Cephaclor, Cefacloro
Cefaclor, sold under the trade name Ceclor among others, is a second-generation cephalosporin antibiotic used to treat certain bacterial infections such as pneumonia and infections of the ear, lung, skin, throat, and urinary tract. It is also available from other manufacturers as a generic.
Chemical data
- Formula
- C15H14ClN3O4S
- Molecular weight
- 367.8 g/mol
- IUPAC name
- (6R,7R)-7-[[(2R)-2-azaniumyl-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- SMILES
- C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)[NH3+])C(=O)[O-])Cl
- InChIKey
- QYIYFLOTGYLRGG-GPCCPHFNSA-N
- XLogP
- -1.1
- Polar surface area
- 142 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
1,949 papers- Cefaclor into the millennium.Journal of chemotherapy (Florence, Italy) · 1999
- Cefaclor revisited.Clinical therapeutics · 2000
- Evaluation of cefaclor.American journal of hospital pharmacy · 1981
- Cefaclor reactions.Pediatric infectious disease · 1985
- Cephalexin, Cefaclor, and Ampicillin: Points in the Picture of β-Lactam Cross-Reactivity.The journal of allergy and clinical immunology. In practice · 2022
via PubMed
~6 min read
Encyclopedic overview
10 sectionsContents
- Medical uses
- Spectrum of activity
- Cautions and contraindications
- Side effects
- Pregnancy and breastfeeding
- Interactions
- Coumarins
- Probenecid
- Antacids
- References
{{Drugbox | Verifiedfields = changed | verifiedrevid = 460022281 | IUPAC_name = (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}- 3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene- 2-carboxylic acid | image = Cefaclor.svg | image_class = skin-invert-image
| tradename = Biocef, Ceclor, Medacef, Distaclor, Keflor, Raniclor | Drugs.com = | MedlinePlus = a682729 | pregnancy_AU = B1 | pregnancy_US = B | legal_status = Rx-only | routes_of_administration = Oral
Excerpted from Wikipedia’s “cefaclor” article, available under the CC BY-SA 4.0 licence.