Structure via PubChem · Public domain (PubChem)
Cefapirin
Sign in to saveAlso known as Cefadyl, Cefa-Lak, (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-{[(pyridin-4-ylsulfanyl)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, CEPR, Cefaprin, Cephapirine, Cephapirin, Cefapirina
chemische Verbindung
Chemical data
- Formula
- C17H17N3O6S2
- Molecular weight
- 423.5 g/mol
- IUPAC name
- (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- SMILES
- CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)CSC3=CC=NC=C3)SC1)C(=O)O
- InChIKey
- UQLLWWBDSUHNEB-CZUORRHYSA-N
- XLogP
- -1.1
- Polar surface area
- 177 Ų
- H-bond donors
- 2
- H-bond acceptors
- 9
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1974
- Admin. routes
- parenteral
- Indications
- bacterial disease
via ChEMBL · EBI
Research
680 papers- Assessment of the Usefulness of Cefapirin and Cefalonium Disks for Susceptibility Testing of Staphylococcus aureus Isolates from Bovine Mastitis.Antibiotics (Basel, Switzerland) · 2020
- Prednisolone and cefapirin act synergistically in resolving experimental Escherichia coli mastitis.Journal of dairy science · 2013
- BestBETs for Vets.The Veterinary record · 2017
- [Cephalosporins].Nederlands tijdschrift voor geneeskunde · 1975
- Ecotoxicity of the two veterinarian antibiotics ceftiofur and cefapirin before and after photo-transformation.The Science of the total environment · 2018
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 423.055877
- Has use
- medication
Show 7 more facts
- defined daily dose
- 4
- chemical formula
- C₁₇H₁₇N₃O₆S₂
- subject has role
- bactericide
- canonical SMILES
- CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CSC3=CC=NC=C3)SC1)C(=O)O
- isomeric SMILES
- CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)CSC3=CC=NC=C3)SC1)C(=O)O
- medical condition treated
- staphylococcal infection
- Commons category
- Cefapirin
Sources (3)
via Wikidata · CC0
Article · Deutsch
Cefapirin ist ein Antibiotikum, welches bei Infektionen durch anfällige Bakterien verwendet wird. Es wird semisynthetisch hergestellt und gehört zur Klasse der Cephalosporine der 1. Generation. Cefapirin ist in Deutschland lediglich für die Verwendung bei Tieren zugelassen, in der Humanmedizin wird es nicht verwendet.
Abstract from DBpedia / Wikipedia · CC BY-SA