Structure via PubChem · Public domain (PubChem)
cefovecin
Sign in to saveCefovecin (INN) is an antibiotic of the cephalosporin class, licensed for the treatment of skin infections in cats and dogs. It is marketed by Zoetis under the trade name Convenia. It is used to treat skin infections caused by Pasteurella multocida in cats, and Staphylococcus intermedius and Streptococcus canis in dogs. The advantage of using a long-acting injectable antibiotic is that, unlike in daily administration, doses cannot be missed. Missed doses may allow partially resistant microbes to recover. The disadvantage is the presence of subtherapeutic concentrations in the weeks after the r
Chemical data
- Formula
- C17H19N5O6S2
- Molecular weight
- 453.5 g/mol
- IUPAC name
- (7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-[(2S)-oxolan-2-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- SMILES
- CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2C3N(C2=O)C(=C(CS3)[C@@H]4CCCO4)C(=O)O
- InChIKey
- ZJGQFXVQDVCVOK-LTRDADOWSA-N
- XLogP
- -0.9
- Polar surface area
- 210 Ų
- H-bond donors
- 3
- H-bond acceptors
- 11
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 453.077675328
Show 5 more facts
- chemical formula
- C₁₇H₁₉N₅O₆S₂
- canonical SMILES
- CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C4CCCO4)C(=O)O
- isomeric SMILES
- CO\N=C(/C(=O)N[C@H]1[C@H]2SCC([C@@H]3CCCO3)=C(N2C1=O)C(O)=O)C4=CSC(N)=N4
- NCI Thesaurus ID
- C76035
- Commons category
- Cefovecin
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
9 sectionsContents
- Medical uses
- Contraindications
- Adverse effects
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Society and culture
- References
- External links
Cefovecin (INN) is an antibiotic of the cephalosporin class, licensed for the treatment of skin infections in cats and dogs. It is marketed by Zoetis under the trade name Convenia. It is used to treat skin infections caused by Pasteurella multocida in cats, and Staphylococcus intermedius and Streptococcus canis in dogs. The advantage of using a long-acting injectable antibiotic is that, unlike in daily administration, doses cannot be missed. Missed doses may allow partially resistant microbes to recover. The disadvantage is the presence of subtherapeutic concentrations in the weeks after the resolution of infections. This is associated with the development of resistance in microbes. It should not be used in pregnant or lactating animals or in animals with a history of allergies to penicillin or cephalosporin drugs.
==Medical uses==
Excerpted from Wikipedia’s “cefovecin” article, available under the CC BY-SA 4.0 licence.