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cefquinome
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cefquinome

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Cefquinome is a fourth-generation cephalosporin with pharmacological and antibacterial properties valuable in the treatment of coliform mastitis and other infections. It is only used in veterinary applications.

~5 min read

Encyclopedic overview

15 sections
Contents
  • Properties
  • Intervet
  • Treatment
  • Clinical usage
  • Human use
  • Veterinary medicine
  • Concerns
  • Resistance and food-borne transmission
  • ''Salmonella''
  • FDA guidelines
  • Synthesis
  • See also
  • References
  • Further reading
  • External links

Cefquinome is a fourth-generation cephalosporin with pharmacological and antibacterial properties valuable in the treatment of coliform mastitis and other infections. It is only used in veterinary applications.

== Properties == Cefquinome is resistant to beta-lactamase. Chemically, its zwitterionic structure can facilitate rapid penetration across biological membranes, including porins of bacterial cell walls. Plus, it has a higher affinity to target penicillin-binding proteins. The reactive site is a beta-lactam nucleus, while the main peripheral functional groups are a quaternary quinolinium, an moiety and an unusual O-alkylated oxime.

Excerpted from Wikipedia’s “cefquinome” article, available under the CC BY-SA 4.0 licence.