cefquinome
Sign in to saveCefquinome is a fourth-generation cephalosporin with pharmacological and antibacterial properties valuable in the treatment of coliform mastitis and other infections. It is only used in veterinary applications.
Article
15 sectionsContents
- Properties
- Intervet
- Treatment
- Clinical usage
- Human use
- Veterinary medicine
- Concerns
- Resistance and food-borne transmission
- ''Salmonella''
- FDA guidelines
- Synthesis
- See also
- References
- Further reading
- External links
Cefquinome is a fourth-generation cephalosporin with pharmacological and antibacterial properties valuable in the treatment of coliform mastitis and other infections. It is only used in veterinary applications.
== Properties == Cefquinome is resistant to beta-lactamase. Chemically, its zwitterionic structure can facilitate rapid penetration across biological membranes, including porins of bacterial cell walls. Plus, it has a higher affinity to target penicillin-binding proteins. The reactive site is a beta-lactam nucleus, while the main peripheral functional groups are a quaternary quinolinium, an moiety and an unusual O-alkylated oxime.