CELSR1

Name

cadherin EGF LAG seven-pass G-type receptor 1

Type

protein-coding

Position

46,360,834–46,537,638 (−)

Aliases

ADGRC1, CDHF9, FMI2, HFMI2, LMPHM9, ME2, YNS

Ensembl

ENSG00000075275

RefSeq RNA

NM_001378328.1, NM_014246.4, XM_011530553.2, XM_011530554.3, XM_011530555.3

RefSeq protein

NP_001365257.1, NP_055061.1, XP_011528855.1, XP_011528856.1, XP_011528857.1

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

cadherin EGF LAG seven-pass G-type receptor 1

Symbol

CELSR1

Biotype

Protein coding

Organism

Homo sapiens

Location

22:46,360,834-46,537,638

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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