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5-hydroxytryptamine receptor 2B
Sign in to saveAlso known as 5-HT 2B receptor, serotonin receptor 2B, 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled, 5-hydroxytryptamine 2B receptor, HTR2B, 5-hydroxytryptamine receptor 2B variant b
mammalian protein found in Homo sapiens
Protein · UniProt
5-hydroxytryptamine receptor 2B
- Gene
- HTR2B
- Organism
- Homo sapiens (Human)
- Length
- 481 aa
- Molecular mass
- 54,298 Da
- Evidence
- 1: Evidence at protein level
G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:18703043, PubMed:23519210, PubMed:7926008, PubMed:8078486, PubMed:8143856, PubMed:8882600). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances (PubMed:12970106, PubMed:18703043, PubMed:23519210, PubMed:23519215, PubMed:24357322, PubMed:28129538, PubMed:30127358, PubMed:36087581, PubMed:7926008, PubMed:8078486, PubMed:8143856). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of d…
Swiss-Prot (reviewed) · via UniProt