CELSR2

Name

cadherin EGF LAG seven-pass G-type receptor 2

Type

protein-coding

Position

109,249,539–109,275,751 (+)

Aliases

ADGRC2, CDHF10, EGFL2, Flamingo1, MEGF3

Ensembl

ENSG00000143126

RefSeq RNA

NM_001408.3

RefSeq protein

NP_001399.1

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

cadherin EGF LAG seven-pass G-type receptor 2

Symbol

CELSR2

Biotype

Protein coding

Organism

Homo sapiens

Location

1:109,249,539-109,275,751

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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