Oxatomide, sold under the brand name Tinset among others, is a antihistamine of the diphenylmethylpiperazine family which is marketed in Europe, Japan, and a number of other countries. It was discovered at Janssen Pharmaceutica in 1975. Oxatomide lacks any anticholinergic effects. In addition to its H1 receptor antagonism, it also possesses antiserotonergic activity similarly to hydroxyzine. Oxatomide was also found to have antiviral activity against Venezuelan equine encephalitis virus (VEEV).
{{Drugbox | Verifiedfields = changed | verifiedrevid = 462266871 | IUPAC_name = 1-{3-[4-(diphenylmethyl)piperazin-1-yl]propyl}-1,3-dihydro-2H-benzimidazol-2-one | image = Oxatomide.png | image_class = skin-invert-image | width = 250px | caption = Above: molecular structure of oxatomide Below: 3D representation of an oxatomide molecule | image2 = Oxatomide 3D.png | image_class2 = bg-transparent
| tradename = Tinset, others | Drugs.com = | pregnancy_category = | legal_status = Rx-only | routes_of_administration = By mouth
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).