oxatomide
Sign in to saveOxatomide, sold under the brand name Tinset among others, is a antihistamine of the diphenylmethylpiperazine family which is marketed in Europe, Japan, and a number of other countries. It was discovered at Janssen Pharmaceutica in 1975. Oxatomide lacks any anticholinergic effects. In addition to its H1 receptor antagonism, it also possesses antiserotonergic activity similarly to hydroxyzine. Oxatomide was also found to have antiviral activity against Venezuelan equine encephalitis virus (VEEV).
Research
248 papers- Oxatomide for stable asthma in adults and children.The Cochrane database of systematic reviews · 2003
- Oxatomide. A review of its pharmacodynamic properties and therapeutic efficacy.Drugs · 1984
- Antiinflammatory effects of oxatomide.Journal of investigational allergology & clinical immunology · 1999
- [Oxatomide: review of pharmacodynamic effects and clinical effects in dermatology].Allergie et immunologie · 1990
- [Protective effect of oxatomide in infantile bronchial asthma. Double-blind study vs placebo].Minerva pediatrica · 1998
via PubMed
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Encyclopedic overview
3 sectionsContents
- Chemistry
- Synthesis
- References
{{Drugbox | Verifiedfields = changed | verifiedrevid = 462266871 | IUPAC_name = 1-{3-[4-(diphenylmethyl)piperazin-1-yl]propyl}-1,3-dihydro-2H-benzimidazol-2-one | image = Oxatomide.png | image_class = skin-invert-image | width = 250px | caption = Above: molecular structure of oxatomide Below: 3D representation of an oxatomide molecule | image2 = Oxatomide 3D.png | image_class2 = bg-transparent
| tradename = Tinset, others | Drugs.com = | pregnancy_category = | legal_status = Rx-only | routes_of_administration = By mouth
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