CFHR3
Sign in to saveAlso known as CFHL3, DOWN16, FHR-3, FHR3, HLF4, complement factor H related 3
Complement factor H-related protein 3 is a protein that in humans is encoded by the CFHR3 gene.
In the Vinony graph
Within Vinony's link graph, CFHR3 is referenced by 2 other articles, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Its subject is documented across 6 Wikipedia language editions.
Gene data
CFHR3- Name
- complement factor H related 3
- Type
- protein-coding
- Position
- 196,774,742–196,803,130 (+)
- Aliases
- CFHL3, DOWN16, FHR-3, FHR3, HLF4
- Ensembl
- ENSG00000116785
- RefSeq RNA
- NM_001166624.2, NM_021023.6
- RefSeq protein
- NP_001160096.1, NP_066303.2
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
complement factor H related 3
- Symbol
- CFHR3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:196,774,742-196,803,130
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 137347
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10878
- genomic end
- 196795407
- genomic start
- 196774813
- chromosome
- human chromosome 1
- cytogenetic location
- 1q31.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Complement factor H-related protein 3 is a protein that in humans is encoded by the CFHR3 gene.
==References==
Excerpted from Wikipedia’s “CFHR3” article, available under the CC BY-SA 4.0 licence.