CHRM2
Sign in to saveAlso known as HM2, cholinergic receptor muscarinic 2
protein-coding gene in the species Homo sapiens
Gene data
CHRM2- Name
- cholinergic receptor muscarinic 2
- Type
- protein-coding
- Position
- 136,868,652–137,020,255 (+)
- Aliases
- HM2
- Ensembl
- ENSG00000181072
- RefSeq RNA
- NM_000739.3, NM_001006626.3, NM_001006627.3, NM_001006628.3, NM_001006629.3
- RefSeq protein
- NP_000730.1, NP_001006627.1, NP_001006628.1, NP_001006629.1, NP_001006630.1
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cholinergic receptor muscarinic 2
- Symbol
- CHRM2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:136,868,593-137,020,255
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Muscarinic receptor M2 coupled to protein G - 6OIK.png
Show 6 more facts
- HomoloGene ID
- 20190
- exact match
- identifiers.org/ncbigene/1129
- genomic end
- 136705002
- genomic start
- 136868652
- cytogenetic location
- 7q33
- Commons category
- Muscarinic acetylcholine receptor M2
via Wikidata · CC0