CLDN3
Sign in to saveAlso known as C7orf1, CPE-R2, CPETR2, HRVP1, RVP1, claudin 3
Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. It is a member of the claudin protein family.
Gene data
CLDN3- Name
- claudin 3
- Type
- protein-coding
- Position
- 73,768,997–73,770,270 (−)
- Aliases
- C7orf1, CPE-R2, CPETR2, HRVP1, RVP1
- Ensembl
- ENSG00000165215
- RefSeq RNA
- NM_001306.4
- RefSeq protein
- NP_001297.1
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 1001
- exact match
- identifiers.org/ncbigene/1365
- genomic start
- 73183328
- genomic end
- 73184600
- cytogenetic location
- 7q11.23
Sources (3)
via Wikidata · CC0
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Article
4 sectionsContents
- Interactions
- References
- External links
- Further reading
Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. It is a member of the claudin protein family.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are composed of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intron-less gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares amino acid sequence similarity with a putative apoptosis-related protein found in rat.