CLDN5
Sign in to saveAlso known as AWAL, BEC1, CPETRL1, TMVCF, claudin 5, TMDVCF
Claudin-5 is a protein that in humans is encoded by the CLDN5 gene. It belongs to the group of claudins.
In the Vinony graph
Vinony's link graph records 8 inbound references to CLDN5, and connects out to PubMed, human chromosome 22 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 22.
Vinony links it to 6 Wikipedia language editions.
Gene data
CLDN5- Name
- claudin 5
- Type
- protein-coding
- Position
- 19,517,452–19,527,545 (−)
- Aliases
- AWAL, BEC1, CPETRL1, TMDVCF, TMVCF
- Ensembl
- ENSG00000184113
- RefSeq RNA
- NM_001130861.1, NM_001363066.2, NM_001363067.2, NM_001426402.1, NM_003277.4
- RefSeq protein
- NP_001124333.1, NP_001349995.1, NP_001349996.1, NP_001413331.1, NP_003268.2
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
claudin 5
- Symbol
- CLDN5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:19,517,452-19,527,545
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 2459
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7122
- chromosome
- human chromosome 22
- genomic end
- 19515068
- genomic start
- 19510547
- cytogenetic location
- 22q11.21
- expressed in
- olfactory bulb
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- External links
- Further reading
Claudin-5 is a protein that in humans is encoded by the CLDN5 gene. It belongs to the group of claudins.
== Function ==
Excerpted from Wikipedia’s “CLDN5” article, available under the CC BY-SA 4.0 licence.