CLDN5
Sign in to saveAlso known as AWAL, BEC1, CPETRL1, TMVCF, claudin 5, TMDVCF
Claudin-5 is a protein that in humans is encoded by the CLDN5 gene. It belongs to the group of claudins.
Gene data
CLDN5- Name
- claudin 5
- Type
- protein-coding
- Position
- 19,523,024–19,527,545 (−)
- Aliases
- AWAL, BEC1, CPETRL1, TMDVCF, TMVCF
- Ensembl
- ENSG00000184113
- RefSeq RNA
- NM_001130861.1, NM_001363066.2, NM_001363067.2, NM_001426402.1, NM_003277.4
- RefSeq protein
- NP_001124333.1, NP_001349995.1, NP_001349996.1, NP_001413331.1, NP_003268.2
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 2459
- exact match
- identifiers.org/ncbigene/7122
- genomic end
- 19515068
- genomic start
- 19510547
- cytogenetic location
- 22q11.21
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- References
- External links
- Further reading
Claudin-5 is a protein that in humans is encoded by the CLDN5 gene. It belongs to the group of claudins.
== Function ==