Structure via PubChem · Public domain (PubChem)
Clindamycin
Sign in to saveAlso known as 7-CDL, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside, 7(S)-chloro-7-deoxylincomycin
chemische Verbindung
OverviewAI-generated
Clindamycin is a chemical compound with the formula C₁₈H₃₃ClN₂O₅S. Its molecular mass is 424.179871, while its weight is listed as 425.0. The substance has a defined daily dose of 0.1.
Chemical properties include an xlogp value of 2.2 and a topological polar surface area of 128. The molecule contains four hydrogen bond donors and seven hydrogen bond acceptors, with a charge of 0. It is referenced by 553 other encyclopedia articles and has 15880 associated entries in PubMed.
Synthesized by Vinony from 18 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- C18H33ClN2O5S
- Molecular weight
- 425 g/mol
- IUPAC name
- (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
- SMILES
- CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl
- InChIKey
- KDLRVYVGXIQJDK-AWPVFWJPSA-N
- XLogP
- 2.2
- Polar surface area
- 128 Ų
- H-bond donors
- 4
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
15,880 papers- Clindamycin.The Medical clinics of North America · 1987
- Clindamycin.Obstetrics and gynecology clinics of North America · 1992
- Clindamycin.The Medical clinics of North America · 1982
- Is clindamycin dangerous?General dentistry · 2017
- Clindamycin--efficacy and toxicity.The Western journal of medicine · 1975
via PubMed
Wikidata facts
- Subclass of
- lincosamides
- Has part
- carbon
- Mass
- 424.179871
- Has use
- medication
Show 10 more facts
- legal status (medicine)
- boxed warning
- chemical formula
- C₁₈H₃₃ClN₂O₅S
- Commons category
- Clindamycin
- medical condition treated
- botulism
- isomeric SMILES
- CCC[C@@H]1C[C@H](N(C1)C)C(=O)NC([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)C(C)Cl
- canonical SMILES
- CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)Cl
- defined daily dose
- 0.1
- subject has role
- essential medicine
- route of administration
- intravaginal administration
- has characteristic
- bitterness
via Wikidata · CC0
Article · Deutsch
Clindamycin ist ein Arzneistoff aus der Gruppe der Lincosamid-Antibiotika. Es ist ein chlorierter Abkömmling von Lincomycin und wird halbsynthetisch hergestellt. Clindamycin wirkt in üblicher Dosierung bakteriostatisch, hochdosiert auch bakterizid hauptsächlich gegen grampositive aerobe Keime, wie Streptokokken oder Staphylokokken, gegen Anaerobier, vor allem gramnegative sowie ferner gegen Chlamydien. In Kombination mit Pyrimethamin ist es gegen Toxoplasma gondii wirksam.
Abstract from DBpedia / Wikipedia · CC BY-SA