CNTF

Name

ciliary neurotrophic factor

Type

protein-coding

Aliases

HCNTF

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010].

via MyGene.info

Gene · Ensembl

ciliary neurotrophic factor

Symbol

CNTF

Biotype

Protein coding

Organism

Homo sapiens

Location

11:58,622,660-58,626,826

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein CNTF PDB 1cnt.png

via Wikidata · CC0