CD21

Also known as complement component (3d/Epstein Barr virus) receptor 2, Epstein-Barr virus receptor, complement receptor type 2, CR2, Complement C3d receptor, complement component 3d receptor 2, EBV receptor

protéine

In the Vinony graph

Vinony's link graph records 456 inbound references to CD21, and connects out to CD8, PubMed and B-cell.

It sits within the topics Complement system and Genes on human chromosome 1.

Vinony links it to 10 Wikipedia language editions.

Protein · UniProt

Complement receptor type 2

Gene: CR2
Organism: Homo sapiens (Human)
Length: 1,033 aa
Molecular mass: 112,916 Da
Evidence: 1: Evidence at protein level

Serves as a receptor for various ligands including complement component CD3d, HNRNPU OR IFNA1 (PubMed:1849076, PubMed:21527715, PubMed:7753047). When C3d is bound to antigens, attaches to C3d on B-cell surface and thereby facilitates the recognition and uptake of antigens by B-cells (PubMed:21527715). This interaction enhances B-cell activation and subsequent immune responses. Forms a complex with several partners on the surface of B-cells including CD19, FCRL5 and CD81, to form the B-cell coreceptor complex that plays a crucial role in B-cell activation and signaling (PubMed:1383329, PubMe…

3D-structureAlternative splicingCell membraneComplement pathwayDirect protein sequencingDisulfide bondGlycoproteinHost cell receptor for virus entry

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Swiss-Prot (reviewed) · via UniProt