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coumarin

File:Coumarin_acsv.svg · Wikimedia Commons · See Wikimedia Commons

EntityQ111812· pop 51· linked from 444 articles

Also known as 2H-benzo[b]pyran-2-one, o-hydroxycinnamic acid delta-lactone, 2-Propenoic acid, 3-(2-hydroxyphenyl)-, delta-lactone, Coumarine, Benzo-alpha-pyrone, chromen-2-one, 2-Oxo-2H-1-Benzopyran, 2-Oxo-1,2-benzopyran

Coumarin () or '2H-chromen-2-one' is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by an unsaturated lactone ring , forming a second six-membered heterocycle that shares two carbons with the benzene ring. It belongs to the benzopyrone chemical class and is considered a lactone.

In the Vinony graph

Within Vinony's link graph, coumarin is referenced by 444 other articles, and connects out to Dipteryx odorata, Cinnamomum verum and vanilla.

It is catalogued under topics including Chembox having GHS data, Coumarins and ECHA InfoCard ID from Wikidata.

Its subject is documented across 50 Wikipedia language editions.

Chemical data

Formula
C9H6O2
Molecular weight
146.14 g/mol
IUPAC name
chromen-2-one
SMILES
C1=CC=C2C(=C1)C=CC(=O)O2
InChIKey
ZYGHJZDHTFUPRJ-UHFFFAOYSA-N
XLogP
1.4
Polar surface area
26.3 Ų
H-bond donors
0
H-bond acceptors
2
Formal charge
0

via PubChem

Wikidata facts

Mass
146.037
Image
Coumarin sample.jpg
Show 6 more facts
canonical SMILES
C1=CC=C2C(=C1)C=CC(=O)O2
chemical formula
C₉H₆O₂
Commons category
Coumarin
density
0.935
melting point
70
boiling point
301
Sources (7)

via Wikidata · CC0

~11 min read

Encyclopedic overview

12 sections
Contents
  • Etymology
  • History
  • Synthesis
  • Biosynthesis
  • Natural occurrence
  • Biological function
  • Metabolism
  • Derivatives
  • Uses
  • Toxicity
  • Notes
  • References

Coumarin () or '2H-chromen-2-one' is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by an unsaturated lactone ring , forming a second six-membered heterocycle that shares two carbons with the benzene ring. It belongs to the benzopyrone chemical class and is considered a lactone.

Coumarin is a colorless crystalline solid with a sweet odor resembling the scent of vanilla and a bitter taste. It is found in many plants, where it may serve as a chemical defense against predators. While coumarin is not an anticoagulant, its 3-alkyl-4-hydroxy derivatives, such as the fungal metabolite dicoumarol, inhibit synthesis of vitamin K, a key component in blood clotting. A related compound, the prescription drug anticoagulant warfarin, is used to inhibit formation of blood clots, deep vein thrombosis, and pulmonary embolism.

Excerpted from Wikipedia’s “coumarin” article, available under the CC BY-SA 4.0 licence.

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