Structure via PubChem · Public domain (PubChem)
crisaborole
Sign in to saveAlso known as AN 2728, AN2728, compound 5b [PMID: 19303290], Eucrisa
Crisaborole, sold under the brand name Eucrisa among others, is a nonsteroidal topical medication used for the treatment of mild-to-moderate atopic dermatitis (eczema) in adults and children.
Chemical data
- Formula
- C14H10BNO3
- Molecular weight
- 251.05 g/mol
- IUPAC name
- 4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile
- SMILES
- B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O
- InChIKey
- USZAGAREISWJDP-UHFFFAOYSA-N
- Polar surface area
- 62.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2016
- Admin. routes
- topical
- Indications
- atopic eczema, psoriasis, localised scleroderma, Eczematoid dermatitis
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 251.075374
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₄H₁₀BNO₃
- canonical SMILES
- B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O
- World Health Organisation international non-proprietary name
- crisaborole
- medical condition treated
- dermatitis
via Wikidata · CC0
~4 min read
Encyclopedic overview
8 sectionsContents
- Side effects
- Medical uses
- Pharmacology
- Pharmacodynamics
- Chemistry
- History
- See also
- References
Crisaborole, sold under the brand name Eucrisa among others, is a nonsteroidal topical medication used for the treatment of mild-to-moderate atopic dermatitis (eczema) in adults and children.
The most common side effects are reactions at the application site (including burning or stinging).
Excerpted from Wikipedia’s “crisaborole” article, available under the CC BY-SA 4.0 licence.