Structure via PubChem · Public domain (PubChem)
oxaceprol
Sign in to saveOxaceprol is an anti-inflammatory drug used in the treatment of osteoarthritis. It is derived from L-proline, a DNA-encoded amino acid. The active effect of Oxaceprol is to inhibit the adhesion and migration of white blood cells.
Chemical data
- Formula
- C7H11NO4
- Molecular weight
- 173.17 g/mol
- IUPAC name
- (2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid
- SMILES
- CC(=O)N1C[C@@H](C[C@H]1C(=O)O)O
- InChIKey
- BAPRUDZDYCKSOQ-RITPCOANSA-N
- XLogP
- -1.1
- Polar surface area
- 77.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- rheumatic disease
via ChEMBL · EBI
Research
37 papers- A systematic review and meta-analysis of oxaceprol in the management of osteoarthritis: An evidence from randomized parallel-group controlled trials.Pharmacological reports : PR · 2019
- Development and characterization of oxaceprol-loaded poly-lactide-co-glycolide nanoparticles for the treatment of osteoarthritis.Drug development research · 2020
- Oxaceprol versus tramadol for knee osteoarthritis: A randomized controlled trial.Indian journal of pharmacology · 2018
- [Meta-analysis of the efficacy of adenosylmethionine and oxaceprol in the treatment of osteoarthritis].Der Orthopade · 2002
- Oxaceprol, an atypical inhibitor of inflammation and joint damage.Pharmacological research · 1996
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 173.069
Show 4 more facts
- canonical SMILES
- CC(=O)N1CC(CC1C(=O)O)O
- chemical formula
- C₇H₁₁NO₄
- isomeric SMILES
- CC(=O)N1C[C@@H](C[C@H]1C(=O)O)O
- melting point
- 132
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Oxaceprol is an anti-inflammatory drug used in the treatment of osteoarthritis. It is derived from L-proline, a DNA-encoded amino acid. The active effect of Oxaceprol is to inhibit the adhesion and migration of white blood cells.
== References ==
Excerpted from Wikipedia’s “oxaceprol” article, available under the CC BY-SA 4.0 licence.
Available in 9 languages
via Wikidata sitelinks · CC0