crystallins
Sign in to saveAlso known as crystallin, Crystallin
thumb|Crystal structure of Duck Delta 1 Crystallin, based on the Protein Data Bank|PDB file 1HY0. In anatomy, a crystallin is a water-soluble structural protein found in the lens and the cornea of the eye accounting for the transparency of the structure. It has also been identified in other places such as the heart, and in aggressive breast cancer tumors. The physical origins of eye lens transparency and its relationship to cataract are an active area of research. Since it has been shown that lens injury may promote nerve regeneration, crystallin has been an area of neural research. So far, it
Key facts
- Protein family.Symbol
- Crystallin
- Protein family.Name
- Beta/Gamma crystallin
- Protein family.Pfam
- PF00030
- Protein family.InterPro
- IPR001064
- Protein family.Prosite
- PDOC00197
- Protein family.SCOP
- 4gcr
via Wikipedia infobox
Research
156,212 papers- Crystallins and Their Complexes.Sub-cellular biochemistry · 2019
- Crystallins in the eye: Function and pathology.Progress in retinal and eye research · 2007
- Effect of lens crystallins aggregation on cataract formation.Experimental eye research · 2025
- Lens crystallins of invertebrates--diversity and recruitment from detoxification enzymes and novel proteins.European journal of biochemistry · 1996
- The Proteome of Cataract Markers: Focus on Crystallins.Advances in clinical chemistry · 2018
via PubMed
Wikidata facts
Show 1 more fact
- Commons category
- Crystallin protein structures
Sources (3)
via Wikidata · CC0
~8 min read
Article
8 sectionsContents
- Function
- Enzyme activity and evolution
- Classification
- Alpha crystallin<span class="anchor" id="Alpha-crystallin"></span>
- Beta and gamma crystallin
- References
- Further reading
- External links
thumb|Crystal structure of Duck Delta 1 Crystallin, based on the Protein Data Bank|PDB file 1HY0. In anatomy, a crystallin is a water-soluble structural protein found in the lens and the cornea of the eye accounting for the transparency of the structure. It has also been identified in other places such as the heart, and in aggressive breast cancer tumors. The physical origins of eye lens transparency and its relationship to cataract are an active area of research. Since it has been shown that lens injury may promote nerve regeneration, crystallin has been an area of neural research. So far, it has been demonstrated that crystallin β b2 (crybb2) may be a neurite-promoting factor.
==Function==