Also known as retinal pigment epithelium-derived rhodopsin homolog
Peropsin, a visual pigment-like receptor, is a protein that in humans is encoded by the RRH gene. It belongs like other animal opsins to the G protein-coupled receptors. Even so, the first peropsins were already discovered in mice and humans in 1997, not much is known about them.
Gene data
RRH- Name
- retinal pigment epithelium-derived rhodopsin homolog
- Type
- protein-coding
- Position
- 109,827,972–109,849,123 (+)
- Ensembl
- ENSG00000180245
- RefSeq RNA
- NM_006583.5
- RefSeq protein
- NP_006574.1
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes opsin 5 and retinal G protein coupled receptor. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
retinal pigment epithelium-derived rhodopsin homolog
- Symbol
- RRH
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:109,827,972-109,849,123
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~4 min read
Encyclopedic overview
6 sectionsContents
- Photochemistry
- Tissue localization
- Gene localization and structure
- Phylogeny
- Clinical significance
- References
Peropsin, a visual pigment-like receptor, is a protein that in humans is encoded by the RRH gene. It belongs like other animal opsins to the G protein-coupled receptors. Even so, the first peropsins were already discovered in mice and humans in 1997, not much is known about them.
== Photochemistry == Like most opsins, peropsins have in its seventh transmembrane domain a lysine corresponding to amino acid position 296 in cattle rhodopsin, which is important for retinal binding and light sensing.
Excerpted from Wikipedia’s “RRH” article, available under the CC BY-SA 4.0 licence.