CYP2A7
Sign in to saveAlso known as CPA7, CPAD, CYP2A, CYPIIA7, P450-IIA4, cytochrome P450 family 2 subfamily A member 7
CYP2A7 (cytochrome P450, family 2, subfamily A, polypeptide 7) is a protein that in humans is encoded by the CYP2A7 gene.
Gene data
CYP2A7- Name
- cytochrome P450 family 2 subfamily A member 7
- Type
- protein-coding
- Position
- 40,873,525–40,882,752 (−)
- Aliases
- CPA7, CPAD, CYP2A, CYPIIA7, P450-IIA4
- Ensembl
- ENSG00000198077
- RefSeq RNA
- NM_000764.3, NM_030589.3, XM_047438279.1, XM_054320014.1, XM_054320015.1
- RefSeq protein
- NP_000755.2, NP_085079.2, XP_047294235.1, XP_054175989.1, XP_054175990.1
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
Cellular component
Pathways
via MyGene.info
Wikidata facts
- Instance of
- gene
Show 5 more facts
- HomoloGene ID
- 85917
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1549
- cytogenetic location
- 19q13.2
- expressed in
- superior frontal gyrus
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
CYP2A7 (cytochrome P450, family 2, subfamily A, polypeptide 7) is a protein that in humans is encoded by the CYP2A7 gene.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
Excerpted from Wikipedia’s “CYP2A7” article, available under the CC BY-SA 4.0 licence.