File:D-sorbitol.svg · Wikimedia Commons · See Wikimedia Commons
Sorbit
Sign in to saveAlso known as D-glucitol, (−)-sorbitol, (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol, D-(-)-sorbitol, (-)-sorbitol, G-ol, Glc-ol, E-420
Arzneistoff
OverviewAI-generated
D-sorbitol is a chemical compound with the formula C₆H₁₄O₆. Its IUPAC name is (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol. The substance has a mass of 182.079 and a melting point of 111. It carries a charge of 0 and features six hydrogen bond donors and six hydrogen bond acceptors.
The compound has an xlogp value of -3.1 and a topological polar surface area of 121. Its canonical SMILES representation is C(C(C(C(C(CO)O)O)O)O)O, while its isomeric SMILES is C([C@H]([C@H]([C@@H]([C@H](CO)O)O)O)O)O. D-sorbitol is referenced by 582 other encyclopedia articles.
Synthesized by Vinony from 20 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- C6H14O6
- Molecular weight
- 182.17 g/mol
- IUPAC name
- (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol
- SMILES
- C([C@H]([C@H]([C@@H]([C@H](CO)O)O)O)O)O
- InChIKey
- FBPFZTCFMRRESA-JGWLITMVSA-N
- XLogP
- -3.1
- Polar surface area
- 121 Ų
- H-bond donors
- 6
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Indications
- pain, Constipation, chronic myelogenous leukemia, bacterial disease
via ChEMBL · EBI
Research
25,143 papers- Identification of catabolic pathway for 1-deoxy-D-sorbitol in Bacillus licheniformis.Biochemical and biophysical research communications · 2022
- D-sorbitol clearance.Digestive diseases and sciences · 1988
- Well-modulated interfacial ion transport enables D-sorbitol/PEDOT:PSS fibers to sense brain electrophysiological signals in vivo.Chemical communications (Cambridge, England) · 2024
- Kit-based synthesis of 2-deoxy-2-[(18)F]-fluoro-D-sorbitol for bacterial imaging.Nature protocols · 2021
- Overcoming NADPH product inhibition improves D-sorbitol conversion to L-sorbose.Scientific reports · 2019
via PubMed
Wikidata facts
- Mass
- 182.079
- Has use
- sweetener
Show 9 more facts
- found in taxon
- Theonella swinhoei
- Commons category
- Sorbitol
- described by source
- Granat Encyclopedic Dictionary
- chemical formula
- C₆H₁₄O₆
- isomeric SMILES
- C([C@H]([C@H]([C@@H]([C@H](CO)O)O)O)O)O
- canonical SMILES
- C(C(C(C(C(CO)O)O)O)O)O
- subject has role
- excipient
- melting point
- 111
- different from
- Sorbit
Sources (8)
via Wikidata · CC0
Article · Deutsch
Sorbit [zɔrˈbiːt] (der Sorbit, auch das Sorbitol, Glucitol oder Hexanhexol) zählt zu den Alditolen (Zuckeralkoholen) und findet in vielen industriell hergestellten Lebensmitteln (Lebensmittelzusatzstoff E 420) als Zuckeraustauschstoff, Trägerstoff sowie Feuchthaltemittel Verwendung. Sorbit ist die reduzierte Polyolform der Hexosen Glucose, Fructose und Sorbose und kann aus diesen durch katalytische oder elektrochemische Hydrierung hergestellt werden.
Abstract from DBpedia / Wikipedia · CC BY-SA