DDX20

Also known as DP103, GEMIN3, DEAD-box helicase 20

Probable ATP-dependent RNA helicase DDX20, also known as DEAD-box helicase 20 and gem-associated protein 3 (GEMIN3), is an enzyme that in humans is encoded by the DDX20 gene.

Gene data

DDX20

Name: DEAD-box helicase 20
Type: protein-coding
Aliases: DP103, GEMIN3

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008].

via MyGene.info

Wikidata facts

Image: Protein DDX20 PDB 2oxc.png

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HomoloGene ID: 5214
exact match: identifiers.org/ncbigene/11218
genomic end: 111775602
genomic start: 111754832
cytogenetic location: 1p13.2

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Contents

Function
Clinical significance
Interactions
References
Further reading

Probable ATP-dependent RNA helicase DDX20, also known as DEAD-box helicase 20 and gem-associated protein 3 (GEMIN3), is an enzyme that in humans is encoded by the DDX20 gene.

== Function ==