Structure via PubChem · Public domain (PubChem)
Dextromoramida
Sign in to saveAlso known as (+)-1-(3-methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidine, (+)-4-(2-methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine, D-2,2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine, R 875, SKF 5137, (+)-2,2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine, (+)-3-methyl-4-morpholino-2,2-diphenyl-1-(pyrrolidin-1-yl)butanone, SKF-5137
compuesto químico
Chemical data
- Formula
- C25H32N2O2
- Molecular weight
- 392.5 g/mol
- IUPAC name
- (3S)-3-methyl-4-morpholin-4-yl-2,2-diphenyl-1-pyrrolidin-1-ylbutan-1-one
- SMILES
- C[C@H](CN1CCOCC1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N4CCCC4
- InChIKey
- INUNXTSAACVKJS-OAQYLSRUSA-N
- XLogP
- 3.8
- Polar surface area
- 32.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
408 papers- Dextromoramide pharmacokinetics following sublingual administration.Palliative medicine · 1996
- Effect of methadone and dextromoramide on dopamine metabolism: comparison with haloperidol and amphetamine.Neuropharmacology · 1975
- Dependence on dextromoramide.British medical journal · 1967
- ADDICTION TO DEXTROMORAMIDE.British medical journal · 1964
- [Dextromoramide (R 875)].Revista medica de Chile · 1959
via PubMed
Wikidata facts
- Subclass of
- DL-moramide
- Mass
- 392.246
Show 8 more facts
- chemical formula
- C₂₅H₃₂N₂O₂
- canonical SMILES
- CC(CN1CCOCC1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N4CCCC4
- Commons category
- Dextromoramide
- isomeric SMILES
- C[C@H](CN1CCOCC1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N4CCCC4
- World Health Organisation international non-proprietary name
- dextromoramide
- subject has role
- narcotic
- MCN code
- 2934.91.23
- defined daily dose
- 40
Sources (3)
via Wikidata · CC0
Article · Español
La dextromoramida es un analgésico opioide aproximadamente tres veces más potente que la morfina pero de más corta duración. Está estructuralmente relacionada con la metadona y se utiliza en el tratamiento del dolor severo.
Abstract from DBpedia / Wikipedia · CC BY-SA