Structure via PubChem · Public domain (PubChem)
diatrizoic acid
Sign in to saveAlso known as Sodium Diatrizoate, Amidotrizoate Sodium, Meglumine Amidotrizoate, Renografin, Hypaque, 3,5-Bis(acetylamino)-2,4,6-triiodobenzoic acid, Triombrin
Diatrizoate, also known as amidotrizoate, Gastrografin, is a contrast agent used during X-ray imaging. This includes visualizing veins, the urinary system, spleen, and joints, as well as computer tomography (CT scan). It is given by mouth, injection into a vein, injection into the bladder, through a nasogastric tube, or rectally.
Key facts
- Drug.image
- Diatrizoic acid.svg
- Drug.image_class
- skin-invert-image
- Drug.alt
- Skeletal formula
- Drug.image2
- Diatrizoic-acid-3D-spacefill.png
- Drug.image_class2
- bg-transparent
- Drug.alt2
- Space-filling model
- Drug.tradename
- Hypaque, Gastrografin, Iothalmate, others
- Drug.ATC_prefix
- V08
- Drug.ATC_suffix
- AA01
- Drug.CAS_number
- 737-31-5
- Drug.PubChem
- 2140
- Drug.DrugBank
- DB00271
- Drug.ChemSpiderID
- 2055
- Drug.UNII
- 5UVC90J1LK
- Drug.UNII2
- V5403H8VG7
- Drug.KEGG
- D02240
- Drug.ChEBI
- 53691
- Drug.ChEMBL
- 1201220
via Wikipedia infobox
Chemical data
- Formula
- C11H9I3N2O4
- Molecular weight
- 613.91 g/mol
- IUPAC name
- 3,5-diacetamido-2,4,6-triiodobenzoic acid
- SMILES
- CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)NC(=O)C)I
- InChIKey
- YVPYQUNUQOZFHG-UHFFFAOYSA-N
- XLogP
- 1.8
- Polar surface area
- 95.5 Ų
- H-bond donors
- 3
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
5,250 papers- Radiocontrast Agent Diatrizoic Acid Induces Mitophagy and Oxidative Stress via Calcium Dysregulation.International journal of molecular sciences · 2019
- Evaluation of the accumulation of the iodinated contrast agents diatrizoic acid and iohexol in Dreissena polymorpha mollusks.Chemosphere · 2023
- Fate and impact at molecular level of diatrizoic acid and iohexol contrast agents in Dreissena polymorpha mollusks.Environmental science and pollution research international · 2024
- The effect of aspirated barium sulfate, iodixanol, and diatrizoic acid on survival and lung injury in a lagomorph model.The Laryngoscope · 2017
- Dry powdered aerosols of diatrizoic acid nanoparticle agglomerates as a lung contrast agent.International journal of pharmaceutics · 2010
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 613.769651
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₁H₉I₃N₂O₄
- canonical SMILES
- CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)NC(=O)C)I
- isomeric SMILES
- C/C(=N\C1=C(C(=C(C(=C1I)C(=O)O)I)/N=C(/O)\C)I)/O
- Commons category
- Diatrizoic acid
- subject has role
- essential medicine
via Wikidata · CC0
~5 min read
Encyclopedic overview
7 sectionsContents
- Medical uses
- Administration
- Contraindications
- Chemistry
- Synthesis
- Brand names
- References
Diatrizoate, also known as amidotrizoate, Gastrografin, is a contrast agent used during X-ray imaging. This includes visualizing veins, the urinary system, spleen, and joints, as well as computer tomography (CT scan). It is given by mouth, injection into a vein, injection into the bladder, through a nasogastric tube, or rectally.
Relatively common side effects include vomiting, diarrhea, and skin redness. Other side effects include itchiness, kidney problems, low blood pressure, and allergic reactions. Diatrizoate is an iodinated ionic radiocontrast agent with high osmolality.
Excerpted from Wikipedia’s “diatrizoic acid” article, available under the CC BY-SA 4.0 licence.