Structure via PubChem · Public domain (PubChem)
gadodiamide hydrate
Sign in to saveAlso known as GDDTPA-BMA, Omniscan, Gadolinium [bis(2-{(carboxylatomethyl)[2-(methylamino)-2-oxoethyl]amino}ethyl)amino]acetate--water (1/1), Gadodiamidum, Gadolinium 5,8-bis(carboxylatomethyl)-11-[2-(methylamino)-2-oxoethyl]-3-oxo-2,5,8,11-tetraazatridecan-13-oate hydrate, Gadodiamida, S-041
Gadodiamide, sold under the brand name Omniscan, is a gadolinium-based MRI contrast agent (GBCA), used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.
In the Vinony graph
Within Vinony's link graph, gadodiamide hydrate is referenced by 65 other articles, and connects out to contrast agent, microparticle and MRI contrast agent.
It is catalogued under topics including Drugboxes which contain changes to verified fields, Drugs with non-standard legal status and MRI contrast agents.
Its subject is documented across 9 Wikipedia language editions.
Chemical data
- Formula
- C16H28GdN5O9
- Molecular weight
- 591.67 g/mol
- IUPAC name
- 2-[bis[2-[carboxylatomethyl-[2-(methylamino)-2-oxoethyl]amino]ethyl]amino]acetate;gadolinium(3+);hydrate
- SMILES
- CNC(=O)CN(CCN(CCN(CC(=O)NC)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].O.[Gd+3]
- InChIKey
- XPCLDSMKWNNKOM-UHFFFAOYSA-K
- Polar surface area
- 189 Ų
- H-bond donors
- 3
- H-bond acceptors
- 12
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1993
- Admin. routes
- parenteral
via ChEMBL · EBI
Research
21 papers- [Comparison of Kinetic Curve between Gadodiamide Hydrate and Gadobutrol on Breast Dynamic Contrast-enhanced Magnetic Resonance Imaging in Invasive Ductal Carcinoma].Nihon Hoshasen Gijutsu Gakkai zasshi · 2018
- Contrast-enhanced MRI of the inner ear after intratympanic injection of meglumine gadopentetate or gadodiamide hydrate.Acta oto-laryngologica · 2011
- Pilot study on indirect magnetic resonance lymphography using gadoxetate disodium in dogs.The Journal of veterinary medical science · 2025
- Significance of Endolymphatic Hydrops in Ears With Unilateral Sensorineural Hearing Loss.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2017
- Prophylactic 0.9% saline hydration inhibited high-dose gadodiamide-induced nephropathy in rats.Human & experimental toxicology · 2012
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 592.113
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₆H₂₈GdN₅O₉
- World Health Organisation international non-proprietary name
- gadodiamide
- canonical SMILES
- CNC(=O)CN(CCN(CCN(CC(=O)NC)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].O.[Gd+3]
- subject has role
- contrast agent
- route of administration
- intravenous infusion and defusion
- legal status (medicine)
- boxed warning
via Wikidata · CC0
~3 min read
Encyclopedic overview
5 sectionsContents
- Medical uses
- Adverse effects
- Hypersensitivity and anaphylaxis
- Society and culture
- References
Gadodiamide, sold under the brand name Omniscan, is a gadolinium-based MRI contrast agent (GBCA), used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.
== Medical uses ==
Excerpted from Wikipedia’s “gadodiamide hydrate” article, available under the CC BY-SA 4.0 licence.
Available in 9 languages
via Wikidata sitelinks · CC0