Structure via PubChem · Public domain (PubChem)
gadodiamide hydrate
Sign in to saveAlso known as GDDTPA-BMA, Omniscan, Gadolinium [bis(2-{(carboxylatomethyl)[2-(methylamino)-2-oxoethyl]amino}ethyl)amino]acetate--water (1/1), Gadodiamidum, Gadolinium 5,8-bis(carboxylatomethyl)-11-[2-(methylamino)-2-oxoethyl]-3-oxo-2,5,8,11-tetraazatridecan-13-oate hydrate, Gadodiamida, S-041
Gadodiamide, sold under the brand name Omniscan, is a gadolinium-based MRI contrast agent (GBCA), used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.
Chemical data
- Formula
- C16H28GdN5O9
- Molecular weight
- 591.67 g/mol
- IUPAC name
- 2-[bis[2-[carboxylatomethyl-[2-(methylamino)-2-oxoethyl]amino]ethyl]amino]acetate;gadolinium(3+);hydrate
- SMILES
- CNC(=O)CN(CCN(CCN(CC(=O)NC)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].O.[Gd+3]
- InChIKey
- XPCLDSMKWNNKOM-UHFFFAOYSA-K
- Polar surface area
- 189 Ų
- H-bond donors
- 3
- H-bond acceptors
- 12
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1993
- Admin. routes
- parenteral
via ChEMBL · EBI
Research
21 papers- [Comparison of Kinetic Curve between Gadodiamide Hydrate and Gadobutrol on Breast Dynamic Contrast-enhanced Magnetic Resonance Imaging in Invasive Ductal Carcinoma].Nihon Hoshasen Gijutsu Gakkai zasshi · 2018
- Contrast-enhanced MRI of the inner ear after intratympanic injection of meglumine gadopentetate or gadodiamide hydrate.Acta oto-laryngologica · 2011
- Pilot study on indirect magnetic resonance lymphography using gadoxetate disodium in dogs.The Journal of veterinary medical science · 2025
- Significance of Endolymphatic Hydrops in Ears With Unilateral Sensorineural Hearing Loss.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2017
- Prophylactic 0.9% saline hydration inhibited high-dose gadodiamide-induced nephropathy in rats.Human & experimental toxicology · 2012
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 592.113
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₆H₂₈GdN₅O₉
- World Health Organisation international non-proprietary name
- gadodiamide
- canonical SMILES
- CNC(=O)CN(CCN(CCN(CC(=O)NC)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].O.[Gd+3]
- subject has role
- contrast agent
- route of administration
- intravenous infusion and defusion
- legal status (medicine)
- boxed warning
via Wikidata · CC0
~3 min read
Encyclopedic overview
5 sectionsContents
- Medical uses
- Adverse effects
- Hypersensitivity and anaphylaxis
- Society and culture
- References
Gadodiamide, sold under the brand name Omniscan, is a gadolinium-based MRI contrast agent (GBCA), used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.
== Medical uses ==
Excerpted from Wikipedia’s “gadodiamide hydrate” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0