Structure via PubChem · Public domain (PubChem)
perflubron
Sign in to saveAlso known as perfluorooctyl bromide, PFOB, 1-bromoperfluorooctane, 1-bromoheptadecafluorooctane, CF3-(CF2)6-CF2-Br, perfluoro-octylbromide
Perflubron (INN/USAN, or perfluorooctyl bromide; brand name Imagent) is a contrast medium for magnetic resonance imaging, computer tomography and sonography. It was approved for this use in the United States by the Food and Drug Administration in 1993.
Chemical data
- Formula
- C8BrF17
- Molecular weight
- 498.96 g/mol
- IUPAC name
- 1-bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane
- SMILES
- C(C(C(C(C(F)(F)Br)(F)F)(F)F)(F)F)(C(C(C(F)(F)F)(F)F)(F)F)(F)F
- InChIKey
- WTWWXOGTJWMJHI-UHFFFAOYSA-N
- XLogP
- 6.9
- Polar surface area
- 0 Ų
- H-bond donors
- 0
- H-bond acceptors
- 17
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1993
- Admin. routes
- oral
- Indications
- bronchopulmonary dysplasia
via ChEMBL · EBI
Research
587 papers- Perflubron emulsion (Oxygent(tm)): a temporary intravenous oxygen carrier.Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS · 2001
- Perflubron emulsion increases subcutaneous tissue oxygen tension in rats.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2006
- Perflubron as an oral contrast agent for MR imaging: results of a phase III clinical trial.Radiology · 1994
- Perfluorocarbon-based oxygen delivery.Artificial cells, blood substitutes, and immobilization biotechnology · 2006
- Perflubron decreases inflammatory cytokine production by human alveolar macrophages.Critical care medicine · 1997
via PubMed
Wikidata facts
- Subclass of
- organobromine compound
- Mass
- 497.891192
Show 5 more facts
- chemical formula
- C₈BrF₁₇
- canonical SMILES
- C(C(C(C(C(F)(F)Br)(F)F)(F)F)(F)F)(C(C(C(F)(F)F)(F)F)(F)F)(F)F
- melting point
- 6
- subject has role
- radiosensitizer
- Commons category
- Perflubron
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Experimental research
- References
Perflubron (INN/USAN, or perfluorooctyl bromide; brand name Imagent) is a contrast medium for magnetic resonance imaging, computer tomography and sonography. It was approved for this use in the United States by the Food and Drug Administration in 1993.
==Experimental research==
Excerpted from Wikipedia’s “perflubron” article, available under the CC BY-SA 4.0 licence.
Gallery (2)
Available in 9 languages
via Wikidata sitelinks · CC0