dithiothreitol
Sign in to saveDithiothreitol (DTT) is an organosulfur compound with the formula . A colorless compound, it is classified as a dithiol and a diol. DTT is redox reagent also known as '''Cleland's reagent''', after W. Wallace Cleland. The reagent is commonly used in its racemic form. Its name derives from the four-carbon sugar, threose. DTT has an epimeric ('sister') compound, dithioerythritol (DTE).
Article
7 sectionsContents
- Synthesis
- Reducing agent
- Applications
- Properties
- See also
- References
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Dithiothreitol (DTT) is an organosulfur compound with the formula . A colorless compound, it is classified as a dithiol and a diol. DTT is redox reagent also known as '''Cleland's reagent''', after W. Wallace Cleland. The reagent is commonly used in its racemic form. Its name derives from the four-carbon sugar, threose. DTT has an epimeric ('sister') compound, dithioerythritol (DTE).
==Synthesis== The traditional route to dithiothreitol (and its isomer dithioerythritol) is sulfidation of the extremely lachrymatory . Modern industrial syntheses instead use related epoxides and hydrogen sulfide.