DnaJ homolog subfamily B member 1 is a protein that in humans is encoded by the DNAJB1 gene.
This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015].
via MyGene.info
DnaJ homolog subfamily B member 1 is a protein that in humans is encoded by the DNAJB1 gene.
A fusion protein of DNAJB1 and PRKACA drives fibrolamellar hepatocellular carcinoma, a type of rare liver cancer.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).