HSPA14

Also known as HSP70-4, HSP70L1, heat shock protein family A (Hsp70) member 14

Heat shock 70 kDa protein 14 also known as HSP70-like protein 1 or heat shock protein HSP60 is a protein that in humans is encoded by the HSPA14 gene.

In the Vinony graph

Within Vinony's link graph, HSPA14 is referenced by 108 other articles, and connects out to Q180686, human chromosome 10 and Ensembl genome database project.

Vinony files it under Genes on human chromosome 10 and Heat shock proteins.

Its subject is documented across 4 Wikipedia language editions.

Gene data

HSPA14

Name: heat shock protein family A (Hsp70) member 14
Type: protein-coding
Position: 14,838,164–14,871,852 (+)
Aliases: HSP70-4, HSP70L1
Ensembl: ENSG00000187522
RefSeq RNA: NM_001037538.1, NM_001278205.1, NM_016299.4, NR_103464.2
RefSeq protein: NP_057383.2

Predicted to enable several functions, including ATP binding activity; misfolded protein binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including cellular response to unfolded protein; chaperone cofactor-dependent protein refolding; and protein refolding. Located in cytosol. Colocalizes with ribosome. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

protein folding protein refolding 'de novo' cotranslational protein folding

Molecular function

protein binding ATP binding ATP hydrolysis activity ATP hydrolysis activity heat shock protein binding protein folding chaperone

Cellular component

nucleus cytoplasm cytosol cytosol cytosol ribosome ribosome membrane

Pathways

Cellular responses to stress Regulation of HSF1-mediated heat shock response Cellular response to heat stress Cellular responses to stimuli Parkin-Ubiquitin Proteasomal System pathway

via MyGene.info

Gene · Ensembl

heat shock protein family A (Hsp70) member 14

Symbol: HSPA14
Biotype: Protein coding
Organism: Homo sapiens
Location: 10:14,838,164-14,871,852
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 6 more facts

HomoloGene ID: 74307
exact match: identifiers.org/ncbigene/51182
cytogenetic location: 10p13
genomic start: 14880163
genomic end: 14913740
Commons category: HSPA14

Sources (5)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

References
Further reading
External links

Heat shock 70 kDa protein 14 also known as HSP70-like protein 1 or heat shock protein HSP60 is a protein that in humans is encoded by the HSPA14 gene.

==References==

Excerpted from Wikipedia’s “HSPA14” article, available under the CC BY-SA 4.0 licence.