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GeneQ18043039· pop 5· linked from 110 articles

BIRC6

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Also known as APOLLON, BRUCE, baculoviral IAP repeat containing 6

Baculoviral IAP repeat-containing protein 6 is a protein that in humans is encoded by the BIRC6 gene.

Gene data

BIRC6
Name
baculoviral IAP repeat containing 6
Type
protein-coding
Position
32,357,019–32,619,582 (+)
Aliases
APOLLON, BRUCE
Ensembl
ENSG00000115760
RefSeq RNA
NM_001378125.1, NM_001446552.1, NM_001446553.1, NM_016252.4, XM_005264450.5
RefSeq protein
NP_001365054.1, NP_001433481.1, NP_001433482.1, NP_057336.3, XP_005264507.2

This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. [provided by RefSeq, Jul 2008].

Gene Ontology

Pathways

Ubiquitin mediated proteolysis - Homo sapiens (human)Apoptosis - multiple species - Homo sapiens (human)DiseaseDiseases of signal transduction by growth factor receptors and second messengersSignaling by ALK in cancerALK mutants bind TKIsSignaling by ALK fusions and activated point mutantsApoptosis Modulation and Signaling

via MyGene.info

Gene · Ensembl

baculoviral IAP repeat containing 6

Symbol
BIRC6
Biotype
Protein coding
Organism
Homo sapiens
Location
2:32,357,019-32,619,582
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

6 sections
Contents
  • Function
  • Interactions
  • Diseases
  • References
  • External links
  • Further reading

Baculoviral IAP repeat-containing protein 6 is a protein that in humans is encoded by the BIRC6 gene.

== Function ==

Excerpted from Wikipedia’s “BIRC6” article, available under the CC BY-SA 4.0 licence.

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