DNAJA1

Name

DnaJ heat shock protein family (Hsp40) member A1

Type

protein-coding

Position

33,025,203–33,041,858 (+)

Aliases

DJ-2, DjA1, HDJ2, HSDJ, HSJ-2, HSJ2, HSPF4, NEDD7, hDJ-2

Ensembl

ENSG00000086061

RefSeq RNA

NM_001314039.2, NM_001539.4

RefSeq protein

NP_001300968.1, NP_001530.1

This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other chromosomes. [provided by RefSeq, Sep 2015].

via MyGene.info

Gene · Ensembl

DnaJ heat shock protein family (Hsp40) member A1

Symbol

DNAJA1

Biotype

Protein coding

Organism

Homo sapiens

Location

9:33,025,203-33,041,858

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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