DNAJA1
Sign in to saveAlso known as DJ-2, DjA1, HDJ2, HSDJ, HSJ2, HSPF4, NEDD7, hDJ-2
DnaJ homolog subfamily A member 1 is a protein that in humans is encoded by the DNAJA1 gene.
Gene data
DNAJA1- Name
- DnaJ heat shock protein family (Hsp40) member A1
- Type
- protein-coding
- Aliases
- DJ-2, DjA1, HDJ2, HSDJ, HSJ-2, HSJ2, HSPF4, NEDD7, hDJ-2
This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other chromosomes. [provided by RefSeq, Sep 2015].
via MyGene.info
Gene · Ensembl
DnaJ heat shock protein family (Hsp40) member A1
- Symbol
- DNAJA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:33,025,203-33,041,858
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 55588
- exact match
- identifiers.org/ncbigene/3301
- genomic end
- 33039905
- genomic start
- 33025273
- cytogenetic location
- 9p21.1
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
DnaJ homolog subfamily A member 1 is a protein that in humans is encoded by the DNAJA1 gene.
==Interactions== DNAJA1 has been shown to interact with PTTG1.