DNAJB4

Name

DnaJ heat shock protein family (Hsp40) member B4

Type

protein-coding

Position

77,979,070–78,019,864 (+)

Aliases

CMYO21, CMYP21, DNAJW, DjB4, HLJ1

Ensembl

ENSG00000162616

RefSeq RNA

NM_001317099.2, NM_001317100.2, NM_001317101.2, NM_001317102.2, NM_001317103.2

RefSeq protein

NP_001304028.1, NP_001304029.1, NP_001304030.1, NP_001304031.1, NP_001304032.1

The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015].

via MyGene.info

Gene · Ensembl

DnaJ heat shock protein family (Hsp40) member B4

Symbol

DNAJB4

Biotype

Protein coding

Organism

Homo sapiens

Location

1:77,979,070-78,019,864

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

via Wikidata · CC0