UBE2N
Sign in to saveAlso known as HEL-S-71, UBC13, UBCHBEN; UBC13, UbcH-ben, UbcH13, ubiquitin conjugating enzyme E2 N, UBCHBEN
Ubiquitin-conjugating enzyme E2 N is a protein that in humans is encoded by the UBE2N gene.
In the Vinony graph
Within Vinony's link graph, UBE2N is referenced by 115 other articles, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 12.
Its subject is documented across 6 Wikipedia language editions.
Gene data
UBE2N- Name
- ubiquitin conjugating enzyme E2 N
- Type
- protein-coding
- Position
- 93,405,673–93,442,263 (−)
- Aliases
- HEL-S-71, UBC13, UBCHBEN, UBCHBEN; UBC13, UbcH-ben, UbcH13
- Ensembl
- ENSG00000177889
- RefSeq RNA
- NM_003348.4
- RefSeq protein
- NP_003339.1
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ubiquitin conjugating enzyme E2 N
- Symbol
- UBE2N
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:93,405,673-93,442,263
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein UBE2N PDB 1j7d.png
Show 8 more facts
- HomoloGene ID
- 128406
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7334
- genomic end
- 93441947
- genomic start
- 93799449
- chromosome
- human chromosome 12
- cytogenetic location
- 12q22
- expressed in
- myocardium
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Ubiquitin-conjugating enzyme E2 N is a protein that in humans is encoded by the UBE2N gene.
== Function ==
Excerpted from Wikipedia’s “UBE2N” article, available under the CC BY-SA 4.0 licence.