MYH8
Sign in to saveAlso known as MyHC-peri, MyHC-pn, gtMHC-F, DA7, myosin, heavy chain 8, skeletal muscle, perinatal, myosin heavy chain 8
Myosin-8 is a protein that in humans is encoded by the MYH8 gene.
Gene data
MYH8- Name
- myosin heavy chain 8
- Type
- protein-coding
- Position
- 10,390,322–10,421,950 (−)
- Aliases
- DA7, MyHC-peri, MyHC-pn, gtMHC-F
- Ensembl
- ENSG00000133020
- RefSeq RNA
- NM_002472.3, XM_054316237.1
- RefSeq protein
- NP_002463.2, XP_054172212.1
Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome. [provided by RefSeq, Sep 2009].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
myosin heavy chain 8
- Symbol
- MYH8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:10,390,322-10,421,950
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Myosin-8 is a protein that in humans is encoded by the MYH8 gene.
Mutations in MYH8 are associated with Trismus pseudocamptodactyly syndrome.
Excerpted from Wikipedia’s “MYH8” article, available under the CC BY-SA 4.0 licence.