MYH8
Sign in to saveAlso known as MyHC-peri, MyHC-pn, gtMHC-F, DA7, myosin, heavy chain 8, skeletal muscle, perinatal, myosin heavy chain 8
Myosin-8 is a protein that in humans is encoded by the MYH8 gene.
In the Vinony graph
Within Vinony's link graph, MYH8 is referenced by 274 other articles, and connects out to hair keratin, PubMed and human chromosome 17.
It is catalogued under the topic Genes on human chromosome 17.
Its subject is documented across 5 Wikipedia language editions.
Gene data
MYH8- Name
- myosin heavy chain 8
- Type
- protein-coding
- Position
- 10,390,322–10,421,950 (−)
- Aliases
- DA7, MyHC-peri, MyHC-pn, gtMHC-F
- Ensembl
- ENSG00000133020
- RefSeq RNA
- NM_002472.3, XM_054316237.1
- RefSeq protein
- NP_002463.2, XP_054172212.1
Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome. [provided by RefSeq, Sep 2009].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
myosin heavy chain 8
- Symbol
- MYH8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:10,390,322-10,421,950
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 68256
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/4626
- genomic end
- 10325267
- genomic start
- 10293639
- chromosome
- human chromosome 17
- cytogenetic location
- 17p13.1
- expressed in
- gastrocnemius muscle
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Myosin-8 is a protein that in humans is encoded by the MYH8 gene.
Mutations in MYH8 are associated with Trismus pseudocamptodactyly syndrome.
Excerpted from Wikipedia’s “MYH8” article, available under the CC BY-SA 4.0 licence.