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GeneQ17916076· pop 6· linked from 813 articles

EGR3

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Also known as EGR-3, PILOT, early growth response 3

Early growth response protein 3 is a protein in humans, encoded by the EGR3 gene.

Gene data

EGR3
Name
early growth response 3
Type
protein-coding
Position
22,687,659–22,693,480 (−)
Aliases
EGR-3, PILOT
Ensembl
ENSG00000179388
RefSeq RNA
NM_001199880.2, NM_001199881.2, NM_004430.3, XM_005273425.4, XM_011544429.3
RefSeq protein
NP_001186809.1, NP_001186810.1, NP_004421.2, XP_005273482.1, XP_011542731.2

This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010].

Gene Ontology

Pathways

C-type lectin receptor signaling pathway - Homo sapiens (human)Hepatitis B - Homo sapiens (human)Viral carcinogenesis - Homo sapiens (human)Signal TransductionSignal TransductionSignaling by NTRKsSignaling by NTRKsSignaling by NTRK1 (TRKA)Signaling by NTRK1 (TRKA)Nuclear Events (kinase and transcription factor activation)

via MyGene.info

Gene · Ensembl

early growth response 3

Symbol
EGR3
Biotype
Protein coding
Organism
Homo sapiens
Location
8:22,687,659-22,693,480
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

3 sections
Contents
  • References
  • Further reading
  • External links

Early growth response protein 3 is a protein in humans, encoded by the EGR3 gene.

The gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controlling biological rhythm. It may also play a role in muscle development.

Excerpted from Wikipedia’s “EGR3” article, available under the CC BY-SA 4.0 licence.

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