ELP2

Also known as SHINC-2, STATIP1, StIP, elongator acetyltransferase complex subunit 2, MRT58

Elongator complex protein 2 is a protein that in humans is encoded by the ELP2 gene. ==Interactions== ELP2 has been shown to interact with STAT3 and Janus kinase 1.

Gene data

ELP2

Name: elongator acetyltransferase complex subunit 2
Type: protein-coding
Position: 36,129,444–36,180,557 (+)
Aliases: MRT58, SHINC-2, STATIP1, StIP
Ensembl: ENSG00000134759
RefSeq RNA: NM_001242875.3, NM_001242876.3, NM_001242877.3, NM_001242878.3, NM_001242879.3
RefSeq protein: NP_001229804.1, NP_001229805.1, NP_001229806.1, NP_001229807.1, NP_001229808.1

The protein encoded by this gene is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin. [provided by RefSeq, May 2016].

Gene Ontology

Biological process

tRNA wobble uridine modification tRNA wobble uridine modification regulation of transcription by RNA polymerase II transcription elongation by RNA polymerase II regulation of translation

Molecular function

RNA polymerase II complex binding protein kinase binding

Cellular component

nucleus nucleoplasm cytoplasm cytoplasm cytosol transcription elongation factor complex elongator holoenzyme complex elongator holoenzyme complex

Pathways

HATs acetylate histones Chromatin modifying enzymes Chromatin organization

via MyGene.info

Wikidata facts

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HomoloGene ID: 6019
genomic end: 33757909
exact match: identifiers.org/ncbigene/55250
genomic start: 33709407
cytogenetic location: 18q12.2

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Further reading

Elongator complex protein 2 is a protein that in humans is encoded by the ELP2 gene. ==Interactions== ELP2 has been shown to interact with STAT3 and Janus kinase 1.

==References==