ELP2

Also known as SHINC-2, STATIP1, StIP, elongator acetyltransferase complex subunit 2, MRT58

Elongator complex protein 2 is a protein that in humans is encoded by the ELP2 gene. ==Interactions== ELP2 has been shown to interact with STAT3 and Janus kinase 1.

In the Vinony graph

Within Vinony's link graph, ELP2 is referenced by 4 other articles, and connects out to PubMed, human chromosome 18 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 18.

Its subject is documented across 6 Wikipedia language editions.

Gene data

ELP2

Name: elongator acetyltransferase complex subunit 2
Type: protein-coding
Position: 36,129,444–36,180,557 (+)
Aliases: MRT58, SHINC-2, STATIP1, StIP
Ensembl: ENSG00000134759
RefSeq RNA: NM_001242875.3, NM_001242876.3, NM_001242877.3, NM_001242878.3, NM_001242879.3
RefSeq protein: NP_001229804.1, NP_001229805.1, NP_001229806.1, NP_001229807.1, NP_001229808.1

The protein encoded by this gene is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin. [provided by RefSeq, May 2016].

Gene Ontology

Biological process

tRNA wobble uridine modification tRNA wobble uridine modification regulation of transcription by RNA polymerase II transcription elongation by RNA polymerase II regulation of translation

Molecular function

RNA polymerase II complex binding protein kinase binding

Cellular component

nucleus nucleus nucleoplasm cytoplasm cytoplasm cytoplasm cytosol transcription elongation factor complex

Pathways

HATs acetylate histones Chromatin modifying enzymes Chromatin organization

via MyGene.info

Gene · Ensembl

elongator acetyltransferase complex subunit 2

Symbol: ELP2
Biotype: Protein coding
Organism: Homo sapiens
Location: 18:36,129,444-36,180,557
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 6019
genomic end: 33757909
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/55250
genomic start: 33709407
chromosome: human chromosome 18
cytogenetic location: 18q12.2
expressed in: canal of the cervix

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

Interactions
References
Further reading

Elongator complex protein 2 is a protein that in humans is encoded by the ELP2 gene. ==Interactions== ELP2 has been shown to interact with STAT3 and Janus kinase 1.

==References==

Excerpted from Wikipedia’s “ELP2” article, available under the CC BY-SA 4.0 licence.