enrofloxacin

Enrofloxacin, sold under the brand name Baytril, among others, is a fluoroquinolone antibiotic used for the treatment of animals. It is a bactericidal agent.

In the Vinony graph

Vinony's link graph records 134 inbound references to enrofloxacin, and connects out to sulfamethazine, quinolone antibiotic and fidaxomicin.

It is catalogued under topics including Carboxylic acids, Cyclopropyl compounds and Drugboxes which contain changes to watched fields.

Vinony links it to 16 Wikipedia language editions.

Chemical data

Formula: C19H22FN3O3
Molecular weight: 359.4 g/mol
IUPAC name: 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxoquinoline-3-carboxylic acid
SMILES: CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F
InChIKey: SPFYMRJSYKOXGV-UHFFFAOYSA-N
XLogP: -0.2
Polar surface area: 64.1 Å²
H-bond donors: 1
H-bond acceptors: 7
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Research

4,425 papers

The enrofloxacin pollution control from fish to environment.Marine pollution bulletin · 2024
Enrofloxacin-The Ruthless Killer of Eukaryotic Cells or the Last Hope in the Fight against Bacterial Infections?International journal of molecular sciences · 2022
Enrofloxacin-associated ocular disease in cats: A scoping review.The Canadian veterinary journal = La revue veterinaire canadienne · 2025
Enrofloxacin: pharmacokinetics and metabolism in domestic animal species.Current drug metabolism · 2013
Formation of inclusion complex of enrofloxacin with 2-hydroxypropyl-β-cyclodextrin.Drug delivery · 2020

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 359.165

Show 5 more facts

chemical formula: C₁₉H₂₂FN₃O₃
canonical SMILES: CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F
Commons category: Enrofloxacin
subject has role: antineoplastic
medical condition treated: bacterial infectious disease

Sources (5)

via Wikidata · CC0

~3 min read

Encyclopedic overview

5 sections

Contents

Activity and susceptibility data
Adverse effects/warnings
Overdosage/acute toxicity
Degradation
References

Enrofloxacin, sold under the brand name Baytril, among others, is a fluoroquinolone antibiotic used for the treatment of animals. It is a bactericidal agent.

The bactericidal activity of enrofloxacin is concentration-dependent, with susceptible bacteria cell death occurring within 20–30 minutes of exposure. Enrofloxacin has demonstrated a significant post-antibiotic effect for both Gram-negative and Gram-positive bacteria and is active in both stationary and growth phases of bacterial replication. Enrofloxacin is partially deethylated by CYP450 into the active metabolite ciprofloxacin, which is also a fluoroquinolone antibiotic.

Excerpted from Wikipedia’s “enrofloxacin” article, available under the CC BY-SA 4.0 licence.