eperezolid

Chemical data

Formula

C18H23FN4O5

Molecular weight

394.4 g/mol

IUPAC name

N-[[(5S)-3-[3-fluoro-4-[4-(2-hydroxyacetyl)piperazin-1-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

SMILES

CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCN(CC3)C(=O)CO)F

InChIKey

SIMWTRCFFSTNMG-AWEZNQCLSA-N

XLogP

-0.3

Polar surface area

102 Ų

H-bond donors

2

H-bond acceptors

7

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

via ChEMBL · EBI

• Oxazolidinones: a review.Drugs · 2000
• In vitro activity of linezolid and eperezolid, two novel oxazolidinone antimicrobial agents, against anaerobic bacteria.Anaerobe · 1997
• Linezolid compared with eperezolid, vancomycin, and gentamicin in an in vitro model of antimicrobial lock therapy for Staphylococcus epidermidis central venous catheter-related biofilm infections.Antimicrobial agents and chemotherapy · 2003
• The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin.Antimicrobial agents and chemotherapy · 1997
• Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions.Antimicrobial agents and chemotherapy · 1997

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

394.165

via Wikidata · CC0