EPHA8

Also known as EEK, EK3, HEK3, EPH receptor A8

Ephrin type-A receptor 8 is a protein that in humans is encoded by the EPHA8 gene.

In the Vinony graph

Vinony's link graph records 120 inbound references to EPHA8, and connects out to Q180686, human chromosome 1 and protein tyrosine kinase.

Vinony files it under Genes on human chromosome 1 and Tyrosine kinase receptors.

Vinony links it to 6 Wikipedia language editions.

Gene data

EPHA8

Name: EPH receptor A8
Type: protein-coding
Position: 22,563,461–22,603,595 (+)
Aliases: EEK, EK3, HEK3
Ensembl: ENSG00000070886
RefSeq RNA: NM_001006943.3, NM_020526.5, XM_011540969.2, XM_011540970.2, XM_011540972.2
RefSeq protein: NP_001006944.1, NP_065387.1, XP_011539271.1, XP_011539272.1, XP_011539274.1

This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. [provided by RefSeq, Jul 2008].