اتینیل استرادیول

Key facts

Drug.Verifiedfields

verified

Drug.Watchedfields

verified

Drug.verifiedrevid

458286647

Drug.image

Ethinylestradiol.svg

Drug.image_class

skin-invert-image

Drug.width

235

Drug.image2

Ethinylestradiol molecule ball.png

Drug.image_class2

bg-transparent

Drug.width2

235

Drug.MedlinePlus

a604032

Drug.routes_of_administration

By mouth, transdermal, vaginal

Drug.class

Estrogen

Drug.ATC_prefix

G03

Drug.ATC_suffix

CA01

Drug.legal_status

Rx-only

Drug.bioavailability

38–48%

Drug.protein_bound

97–98% (to albumin; is not bound to )

Drug.metabolism

Liver (primarily CYP3A4)

via Wikipedia infobox

Chemical data

Formula

C20H24O2

Molecular weight

296.4 g/mol

IUPAC name

(8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol

SMILES

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)O

InChIKey

BFPYWIDHMRZLRN-SLHNCBLASA-N

XLogP

3.7

Polar surface area

40.5 Ų

H-bond donors

2

H-bond acceptors

2

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

1982

Admin. routes

oral, topical

Indications

neoplasm, chronic lymphocytic leukemia, polycystic ovary syndrome, HIV infection

via ChEMBL · EBI

• Low-dose ethinylestradiol/levonorgestrel.Drugs · 2005
• Ethinylestradiol/dienogest in oral contraception.Drugs · 2010
• Ethinylestradiol/Chlormadinone acetate: dermatological benefits.American journal of clinical dermatology · 2011
• Transdermal ethinylestradiol/norelgestromin: a review of its use in hormonal contraception.Treatments in endocrinology · 2003
• Ethinylestradiol/drospirenone: a review of its use as an oral contraceptive.Treatments in endocrinology · 2003

via PubMed

Wikidata facts

Subclass of

steroid

Mass

296.178

Has use

medication

via Wikidata · CC0