Structure via PubChem · Public domain (PubChem)
etomidato
Sign in to saveAlso known as Amidate®, D-etomidate, R 16659, (R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester, (+)-ethyl 1-(alpha-methylbenzyl)imidazole-5-carboxylate, R-(+)-ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate, (R)-(+)-1-(alpha-methylbenzyl)imidazole-5-carboxylic acid ethyl ester, (+)-etomidate
composto químico
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 457797420
- Drug.image
- File:Etomidate.svg
- Drug.image_class
- skin-invert-image
- Drug.caption
- Above: molecular structure of (R)-etomidate Below: 3D representation of an etomidate molecule
- Drug.image2
- Etomidate 3D Ball-and-Stick.png
- Drug.image_class2
- bg-transparent
- Drug.width
- 150
- Drug.tradename
- Amidate, Hypnomidate, Tomvi
- Drug.DailyMedID
- Etomidate
- Drug.routes_of_administration
- Intravenous
- Drug.ATC_prefix
- N01
- Drug.ATC_suffix
- AX07
- Drug.legal_AU
- S4
- Drug.legal_BR
- C1
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.legal_UK
- POM
via Wikipedia infobox
Chemical data
- Formula
- C14H16N2O2
- Molecular weight
- 244.29 g/mol
- IUPAC name
- ethyl 3-[(1R)-1-phenylethyl]imidazole-4-carboxylate
- SMILES
- CCOC(=O)C1=CN=CN1[C@H](C)C2=CC=CC=C2
- InChIKey
- NPUKDXXFDDZOKR-LLVKDONJSA-N
- XLogP
- 3
- Polar surface area
- 44.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
3,465 papers- Evaluation of Etomidate Use and Association with Mortality Compared with Ketamine among Critically Ill Patients.American journal of respiratory and critical care medicine · 2024
- Etomidate.Lancet (London, England) · 1983
- Novel etomidate derivatives.Current pharmaceutical design · 2012
- [Etomidate--propofol].Klinische Anasthesiologie und Intensivtherapie · 1993
- Etomidate as an Induction Agent in Sepsis.Critical care nursing clinics of North America · 2018
via PubMed
Wikidata facts
- Subclass of
- heterocyclic compound
- Has part
- oxygen
- Mass
- 244.121178
- Has use
- medication
Show 7 more facts
- medical condition treated
- brain ischemia
- Commons category
- Etomidate
- chemical formula
- C₁₄H₁₆N₂O₂
- route of administration
- intravenous infusion and defusion
- World Health Organisation international non-proprietary name
- etomidate
- isomeric SMILES
- CCOC(=O)C1=CN=CN1[C@H](C)C2=CC=CC=C2
- canonical SMILES
- CCOC(=O)C1=CN=CN1C(C)C2=CC=CC=C2
via Wikidata · CC0
Article · Português
Etomidato é um fármaco anestésico hipnótico de curta ação administrado por via endovenosa geralmente utilizado em indução de anestesia geral. É utilizado em procedimentos rápidos como redução de fraturas e cardioversão. Foi descoberto em 1964. Algumas de suas particularidades são a estabilidade cardiovascular e a inibição do eixo hipotálamo hipofisário quando administrado em infusão contínua. Diminui a pressão intracraniana. Não libera histamina e sua dose letal é 16 vezes maior do que a dose terapêutica.
Abstract from DBpedia / Wikipedia · CC BY-SA