Structure via PubChem · Public domain (PubChem)
依托咪酯
Sign in to saveAlso known as Amidate®, D-etomidate, R 16659, (R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester, (+)-ethyl 1-(alpha-methylbenzyl)imidazole-5-carboxylate, R-(+)-ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate, (R)-(+)-1-(alpha-methylbenzyl)imidazole-5-carboxylic acid ethyl ester, (+)-etomidate
药品
In the Vinony graph
Within Vinony's link graph, 依托咪酯 is referenced by 908 other articles, and connects out to ginkgolide, benzodiazepine drug and picrotoxin.
Vinony files it under 11β-Hydroxylase inhibitors, Belgian inventions and Chemical substances for emergency medicine.
Its subject is documented across 27 Wikipedia language editions.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 457797420
- Drug.image
- File:Etomidate.svg
- Drug.image_class
- skin-invert-image
- Drug.caption
- Above: molecular structure of (R)-etomidate Below: 3D representation of an etomidate molecule
- Drug.image2
- Etomidate 3D Ball-and-Stick.png
- Drug.image_class2
- bg-transparent
- Drug.width
- 150
- Drug.tradename
- Amidate, Hypnomidate, Tomvi
- Drug.DailyMedID
- Etomidate
- Drug.routes_of_administration
- Intravenous
- Drug.ATC_prefix
- N01
- Drug.ATC_suffix
- AX07
- Drug.legal_AU
- S4
- Drug.legal_BR
- C1
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.legal_UK
- POM
via Wikipedia infobox
Chemical data
- Formula
- C14H16N2O2
- Molecular weight
- 244.29 g/mol
- IUPAC name
- ethyl 3-[(1R)-1-phenylethyl]imidazole-4-carboxylate
- SMILES
- CCOC(=O)C1=CN=CN1[C@H](C)C2=CC=CC=C2
- InChIKey
- NPUKDXXFDDZOKR-LLVKDONJSA-N
- XLogP
- 3
- Polar surface area
- 44.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- parenteral
- Indications
- hypertension, stroke, respiratory failure
via ChEMBL · EBI
Research
3,465 papers- Evaluation of Etomidate Use and Association with Mortality Compared with Ketamine among Critically Ill Patients.American journal of respiratory and critical care medicine · 2024
- Etomidate.Lancet (London, England) · 1983
- Novel etomidate derivatives.Current pharmaceutical design · 2012
- [Etomidate--propofol].Klinische Anasthesiologie und Intensivtherapie · 1993
- Etomidate as an Induction Agent in Sepsis.Critical care nursing clinics of North America · 2018
via PubMed
Wikidata facts
- Subclass of
- heterocyclic compound
- Has part
- oxygen
- Mass
- 244.121178
- Has use
- medication
Show 7 more facts
- medical condition treated
- brain ischemia
- Commons category
- Etomidate
- chemical formula
- C₁₄H₁₆N₂O₂
- route of administration
- intravenous infusion and defusion
- World Health Organisation international non-proprietary name
- etomidate
- isomeric SMILES
- CCOC(=O)C1=CN=CN1[C@H](C)C2=CC=CC=C2
- canonical SMILES
- CCOC(=O)C1=CN=CN1C(C)C2=CC=CC=C2
via Wikidata · CC0
Article · 中文
依托咪酯（英語：etomidate），别名R-(+)-1-(1-苯乙基)-1-氢-咪唑-5-甲酸乙酯、(R)-(+)-1-(1-苯乙基)-1-氢-咪唑-5-甲酸乙酯、(R)-1-(1-苯基乙基)-1H-咪唑-5-甲酸乙酯、乙苄咪唑。是一种，用于诱导全身麻醉。
Abstract from DBpedia / Wikipedia · CC BY-SA