exonuclease
Sign in to savethumb|200px|3′ to 5′ Exonuclease associated with Pol I
In the Vinony graph
Within Vinony's link graph, exonuclease is referenced by 586 other articles, and connects out to enzyme, RecBCD and exoribonuclease.
Vinony files it under EC 3.1 and Genetics techniques.
Its subject is documented across 28 Wikipedia language editions.
Research
16,198 papers- Exonuclease-based aptasensors: Promising for food safety and diagnostic aims.Talanta · 2023
- Single 3'-exonuclease-based multifragment DNA assembly method (SENAX).Scientific reports · 2022
- Non-Exonuclease Domain POLE Mutations Associated with Immunotherapy Benefit.The oncologist · 2022
- Mre11 exonuclease activity promotes irreversible mitotic progression under replication stress.Life science alliance · 2022
- Exonuclease EXD2 in mitochondrial translation.Nature cell biology · 2018
via PubMed
Wikidata facts
Show 2 more facts
- Commons category
- Exonucleases
- EC enzyme number
- 3.1.-.-
Sources (2)
via Wikidata · CC0
~6 min read
Encyclopedic overview
8 sectionsContents
- Significance to polymerase
- ''E. coli'' types
- dnaQ
- Discoveries in humans
- Discoveries in yeast
- Discoveries in Coronaviruses
- References
- External links
thumb|200px|3′ to 5′ Exonuclease associated with Pol I
Exonucleases are enzymes that work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain. A hydrolyzing reaction that breaks phosphodiester bonds at either the 3′ or the 5′ end occurs. Its close relative is the endonuclease, which cleaves phosphodiester bonds in the middle (endo) of a polynucleotide chain. Eukaryotes and prokaryotes have three types of exonucleases involved in the normal turnover of mRNA: 5′ to 3′ exonuclease (Xrn1), which is a dependent decapping protein; 3′ to 5′ exonuclease, an independent protein; and poly(A)-specific 3′ to 5′ exonuclease.
Excerpted from Wikipedia’s “exonuclease” article, available under the CC BY-SA 4.0 licence.