FCMR
Sign in to saveAlso known as TOSO, FAIM3, Fc fragment of IgM receptor, Fc mu receptor, FcmuR
Fc fragment of IgM receptor is a protein that in humans is encoded by the FCMR gene.
Gene data
FCMR- Name
- Fc mu receptor
- Type
- protein-coding
- Position
- 206,903,317–206,923,247 (−)
- Aliases
- FAIM3, FcmuR, IgM FcR, TOSO
- Ensembl
- ENSG00000162894
- RefSeq RNA
- NM_001142472.1, NM_001142473.2, NM_001193338.2, NM_001405862.1, NM_001405863.1
- RefSeq protein
- NP_001135945.1, NP_001180267.1, NP_001392791.1, NP_001392792.1, NP_001392793.1
Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010].
Gene Ontology
Biological process
immunoglobulin transcytosis in epithelial cellshumoral immune response mediated by circulating immunoglobulincellular defense responsesignal transductionFc receptor signaling pathwaynegative regulation of apoptotic processregulation of B cell receptor signaling pathwayFc receptor-mediated immune complex endocytosis
Molecular function
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 48347
- exact match
- identifiers.org/ncbigene/9214
- cytogenetic location
- 1q32.1
- genomic start
- 206903317
- genomic end
- 207096592
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Fc fragment of IgM receptor is a protein that in humans is encoded by the FCMR gene.
==Function==
Connections
Q180686
Entity
human chromosome 1
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Ensembl genome database project
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protein
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Wikidata
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gene
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chromosome
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public domain
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digital object identifier
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antibody
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human genome
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base pair
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locus
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gene expression
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Online Mendelian Inheritance in Man
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United States National Library of Medicine
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immunoglobulin M
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Entrez
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Q905695
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GeneCards
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