File:Finasteride.svg · Wikimedia Commons · See Wikimedia Commons
finasterida
Sign in to saveAlso known as MK 906, MK-906, MK906, (5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
composto químico
OverviewAI-generated
Finasteride is a chemical compound with the formula C₂₃H₃₆N₂O₂. Its molecular mass is listed as 372.278, while its weight is recorded as 372.5. The substance has a defined daily dose of 5.
Chemical properties include an xlogp value of 3 and a topological polar surface area of 58.2. The molecule contains two hydrogen bond donors and two hydrogen bond acceptors, with a charge of 0. It is associated with a PubMed query count of 4080 and is referenced by 465 other encyclopedia articles.
Synthesized by Vinony from 18 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 458461973
- Drug.image
- Finasteride.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.image2
- Finasteride-from-xtal-3D-bs-17.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 250
- Drug.tradename
- Proscar, Propecia, Finide, others
- Drug.MedlinePlus
- a698016
- Drug.DailyMedID
- Finasteride
- Drug.pregnancy_AU
- X
- Drug.routes_of_administration
- By mouth, topical
- Drug.class
- 5α-Reductase inhibitor
- Drug.ATC_prefix
- G04
- Drug.ATC_suffix
- CB01
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
via Wikipedia infobox
Chemical data
- Formula
- C23H36N2O2
- Molecular weight
- 372.5 g/mol
- IUPAC name
- (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
- SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC(C)(C)C)CC[C@@H]4[C@@]3(C=CC(=O)N4)C
- InChIKey
- DBEPLOCGEIEOCV-WSBQPABSSA-N
- XLogP
- 3
- Polar surface area
- 58.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
4,080 papers- Comparison of oral minoxidil, finasteride, and dutasteride for treating androgenetic alopecia.The Journal of dermatological treatment · 2022
- Finasteride for hair loss: a review.The Journal of dermatological treatment · 2022
- Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a phase III, randomized, controlled clinical trial.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022
- Risk of Depression Associated With Finasteride Treatment.Journal of clinical psychopharmacology · 2021
- Sexual side effects of 5-α-reductase inhibitors finasteride and dutasteride: A comprehensive review.Dermatology online journal · 2017
via PubMed
Article · Português
Finasterida (também conhecido como Proscar, Propecia, Fincar, Finalop, Finpecia, Finax, Finast, Finara, Prosteride) é um medicamento antiandrógeno inibidor da 5-alfarredutase, a enzima que converte a testosterona em di-hidrotestosterona. É usado em baixas doses para o tratamento da calvície e em altas doses no tratamento da hiperplasia prostática benigna e câncer de próstata.
Abstract from DBpedia / Wikipedia · CC BY-SA